Description

Poly(N-isopropylacrylamide) (PNIPAM) Thermoresponsive Hydrogel is a well-established smart biomaterial that exhibits a sharp phase transition near physiological temperature (~32°C). Below its lower critical solution temperature (LCST), the hydrogel remains hydrated and swollen, while above this temperature it rapidly collapses and expels water. This reversible transition enables dynamic control over material structure and function.

The system is widely used for applications requiring temperature-triggered behavior, including controlled drug release, cell sheet engineering, and responsive coatings. Its properties can be tuned through copolymerization or crosslinking density adjustments, allowing precise control over transition temperature and mechanical characteristics. The material is optimized for reproducibility and compatibility with advanced biomaterial systems.

Key features
Temperature-responsive phase transition
Reversible swelling and collapse behavior
LCST near physiological temperature
Tunable responsiveness
Compatible with functionalization

Typical specifications
Volume 20 mL
Polymer poly(N-isopropylacrylamide) (PNIPAM)
Transition temperature ~32°C
Response reversible
Sterility available upon request

Applications
Smart drug delivery systems
Cell sheet engineering
Responsive coatings
Bioactuators
Advanced biomaterials research