Description

Poly(acrylic acid) (PAA) pH-Responsive Hydrogel is a smart biomaterial designed to respond dynamically to changes in pH. The polymer contains ionizable carboxylic acid groups that become charged at higher pH, causing electrostatic repulsion and swelling of the hydrogel network. At lower pH, the network collapses due to protonation, enabling reversible structural transitions.

This behavior allows precise control over drug release, permeability, and mechanical properties in response to environmental conditions. The system is widely used in targeted delivery applications, particularly in environments with varying pH such as the gastrointestinal tract. The hydrogel properties can be tuned through crosslinking density and polymer composition to achieve desired responsiveness.

Key features
pH-responsive swelling behavior
Reversible expansion and contraction
Ionizable functional groups
Tunable response range
Compatible with functionalization

Typical specifications
Volume 20 mL
Polymer poly(acrylic acid) (PAA)
Response pH-dependent swelling
pKa ~4.5–5.5
Sterility available upon request

Applications
Targeted drug delivery
Smart coatings
Controlled release systems
Biosensing platforms
Environmental responsive materials